This article discusses a collection of nine volumes titled *Medicine Records of Ancient Masters (二集自序)*, focusing on rare and precious traditional Chinese medicine manuscripts from the Ming and Qing dynasties. The text highlights the significance of these documents in preserving historical medical knowledge and their contribution to modern research. It emphasizes the meticulous editing and curation process behind the compilation of these孤本精选, making them an invaluable resource for scholars and enthusiasts of traditional Chinese medicine.